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graft-vs.-host disease
"GvH" seen in recipients of bone marrow allografts
- small bowel & other GI sites:
- thickened wall
- mucosal folds thickened or effaced
- increased secretions ==> rapid transit of GI tract
- mass ==> focal edema, fibrosis
- "hallmark":
- diffuse, uniform thickening of SB
- "toothpaste" SB
- also affects skin, liver, lymphoid system
Charles E. Kahn, Jr., MD - 2 February 1995
Last updated: 1 September 2006
Medical College of Wisconsin