Crohn disease: extraintestinal manifestations

fatty liver
gallstones (28-34%)
- risk 3-5X higher than expected
- secondary to malabsorption of bile salts in terminal ileum
- correlation with length of diseased ileum and duration of disease
sclerosing cholangitis
bile duct carcinoma
amyloidosis
urolithiasis: oxalate/uric acid stones
migratory arthritis (5-20%), sacroilitis, ankylosing spondylitis
erythema nodosum, uveitis

Yong H. Hahn, MD - 2 February 1995
Last updated: 1 September 2006