CHORUS

Collaborative Hypertext of Radiology

Musculoskeletal system

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hemophilia

• incidence: knees > elbows > ankles > hips > shoulders > wrists

• results in secondary OA (DDx: acromegaly, ochronosis, spondyloepiphyseal dysplasia, chronic trauma)

xray manifestations:

• premature closure of epiphysis leading to short bone with enlarged end
• "squared" patella (flattened inferiorly)
• widened intercondylar notch
• subchondral cysts
• severe osteopenia

Cf: JRA

Related CHORUS documents: progeria (Hutchinson-Gilford) syndrome achondroplasia spondyloepiphyseal dysplasia Hurler's syndrome blue rubber bleb nevus syndrome acromegaly