Cronkhite-Canada syndrome

• not inherited; no pattern
• inflammatory glandular dilatation of stomach, colon, SB (50%)
• juvenile-type polyps

• no malignant potential
• protein and electrolyte loss
• ectodermal abnormalities
  • alopecia
  • hyperpigmentation
  • nail loss (onycholysis)

• prognosis:
  • males: remits
  • females: die in 6-18 months d/t cachexia

see: polyposis syndromes

© 2002, C.E. Kahn, Jr.
2002-04-18