fibrous dysplasia

• xray: "ground glass" lesion with sclerotic rim
• may be expansile, predominantly metaphysis to diaphysis
• labs: increased alk phos, o/w normal

• monostotic form
  • any bone (ribs, femur, tibia most common)
  • diametaphyseal

• polyostotic form
  • unilateral predominance
  • not familial (except cherubism)
  • scalloping, expansion, deformity (Sheperd's crook)

• other forms
  • McCune-Albright syndrome (with precocious puberty)
  • leontiasis ossea (involves skull and facial bones)
  • cherubism (hereditary form, involves mandible)

© 2002, C.E. Kahn, Jr.
2002-04-18