graft-vs.-host disease

• small bowel & other GI sites:
  • thickened wall
  • mucosal folds thickened or effaced
  • increased secretions ==> rapid transit of GI tract
  • mass ==> focal edema, fibrosis

• "hallmark":
  • diffuse, uniform thickening of SB
  • "toothpaste" SB

• also affects skin, liver, lymphoid system

© 2002, C.E. Kahn, Jr.
2002-04-18