multiple endocrine neoplasia (MEN)
autosomal dominant syndromes (occ. sporadic)
- APUD (amine precursor uptake and decarboxylation) system
- probable neural crest origin
- type 1
- three P's: pituitary, parathyroid, pancreas
- Wermer syndrome
- type 2
- medullary thyroid, "medullary adrenal" (pheo),
parathyroid
- Sipple syndrome
- type 3
- marfanoid ("type 2-B")
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© 2002, C.E. Kahn, Jr.
2002-04-18