sarcoidosis

• unknown etiology
• young adults, blacks > whites
• prognosis usually good

• may affect any organ
• chest most often involved
• diffuse pulmonary infiltrate, may resolve or progress to fibrosis
  • HRCT:
    • mediastinal adenopathy
    • early = septal thickening, peribronchovascular nodules, alveolitis, ground-glass opacity
    • late = traction bronchiectasis, fibrosis, honeycombing
• skeleton involved in 10%

• Dx: bronchial/transbronchial biopsy (60-95% diagnostic), liver or scalene bx, Kveim test

© 2002, C.E. Kahn, Jr.
2002-04-18