spontaneous osteolysis

several syndromes of "vanishing bones": (Cf: rapid demineralization)

idiopathic hereditary osteolysis
- autosomal dominant, manifest in early childhood
- carpals + tarsals involved first
autosomal-recessive carpal and tarsal osteolysis
idiopathic osteolysis with nephropathy
- carpals, tarsals, adjacent tubular bones involved
- azotemia --> death in early adulthood
massive osteolysis of Gorham
- angiomatous destruction