tuberous sclerosis (Bourneville disease)

• calcified subependymal hamartomas
• uncalcified tubers in cerebral cortex
• enhancing lesion ==> malignant transformation to
  giant cell astrocytoma

• skin lesions
• angiomyolipoma
• increased risk of renal cell Ca

© 2002, C.E. Kahn, Jr.
2002-04-18