glioblastoma multiforme (GBM)

"grade IV astrocytoma"

invasive, malignant glioma of astrocytic origin
most common supratentorial glioma (40%)
40-60 y.o.
may occur anywhere in the brain
commonly spreads across corpus callosum
CT findings:
- tumor margin slightly higher density than brain
- finger-like projections of low density (edema)
- marked enhancement with contrast