oxalosis
rare inborn error of metabolism (autosomal recessive)
- excessive amounts of oxalic acid combine with calcium and deposit
throughout the body (kidney, soft tissue, bone)
- early death in childhood
findings:
- hyperoxaluria (> 50 mg/day in urine)
- progressive renal failure
- osteoporosis
- erosions on concave side of metaphysis near epiphysis
- bone-within-bone appearance of spine
- medullary nephrocalcinosis
"secondary hyperoxaluria" or enteric hyperoxaluria
- secondary to disturbance of bile acid metabolism:
i.e., s/p jejunal bypass, ileal resection, blind loop
syndrome, Crohn's, increased ingestion of green
leafy vegetables, pyridoxine deficiency, etc.
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© 2002, C.E. Kahn, Jr.
2002-04-18