Sjogren syndrome

chronic systematic inflammatory disorder of unknown etiology characterized by dryness of mucous membranes

primary Sjogren syndrome:
- without underlying autoimmune disease
- recurrent parotitis in children
- sicca syndrome (xerophthalmia and xerostomia)
secondary Sjogren syndrome:
- connective tissue diseases (RA, SLE, PSS, psoriasis, etc)
- lymphoprolifertive disorders (lymphocytic interstitial pneumonitis, pseudolymphoma, lymphoma, Waldenstrom macroglobulinemia)

Findings:

CXR: reticulododular pattern, patchy consolidation/atelactisis, pneumonitis, +/- pleural effusion
U/S: multiple scattered parotid cysts bilaterally
enlarged lacrimal glands