neuroblastoma
- most common solid abdominal mass of infancy (12% of all perinatal neoplasms)
- 3rd most common malignancy in infancy (after leukemia and CNS tumors)
- 2nd most common tumor in children (Wilms more common in older kids)
location: anywhere within sympathetic neural chain
- adrenal gland (36%): bilateral in 7-10%
- extraadrenal in sympathetic chain (18%)
- thorax and posterior mediastinum (14%)
- neck (5%); pelvis (5%)
- skull, olfactory bulb, cerebellum, cerebrum: (2%)
- other sites (10%); unknown primary (10%)
metastasis: bone (60%); regional nodes (42%); liver (15%);
intracranial (14%); lung (10%)
see also: Hutchinson, Pepper, and blueberry muffin syndromes
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© 2002, C.E. Kahn, Jr.
2002-04-18