hemophilia

incidence: knees > elbows > ankles > hips > shoulders > wrists
results in secondary OA (DDx: acromegaly, ochronosis, spondyloepiphyseal dysplasia, chronic trauma)

xray manifestations:

premature closure of epiphysis leading to short bone with enlarged end
"squared" patella (flattened inferiorly)
widened intercondylar notch
subchondral cysts
severe osteopenia

Cf: JRA

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© 2002, C.E. Kahn, Jr.
2002-04-18