rubella

• fetus susceptable to virus in 1st trimester

clinical manifestations:

• skeletal
  • celery stalk metaphysis
  • limb bones less well mineralized
  • NO periostitis (findings usually persist for 1-2 mos)
• low birth weight
• eye abnormalities
  • cataracts
  • glaucoma
  • retinitis
• deafness
• brain abnormalities
  • microcephaly
  • hydrocephalus
  • meningoencephalitis
• cardiac defects
  • PDA
  • VSD
• thrombocytopenic purpura
• hepatosplenomegaly with hepatitis and jaundice
• pneumonia

© 2002, C.E. Kahn, Jr.
2002-04-18