amyloidosis: bone manifestations

• joint pain without radiographic findings
• osteoporosis, esp. in axial skeleton
• lytic lesions that destroy cortex and invade soft tissue
• wrist
  • scaphoid and lunate lesions that may extend into the carpal tunnel
  • inducing the classic complaints of carpal tunnel syndrome

amyloid arthropathy DDx:

• pigmented villonodular synovitis
• synovial chondromatosis
• rheumatoid arthritis
• TB

© 2002, C.E. Kahn, Jr.
2002-04-18